PG seems like a really smart guy. He was able to point put the pain points with very litter background information. He reminded me something my college professor used to tell me "Always try to surround yourself with someone smarter than you". I wish I know more people as smart as him.
There are about 5 questions that feed into "who is going to pay you?" All of them are pain points for the vast majority of startups (anecdata). Idea + development + customers = Business. I'm not saying PG is a dope or anything, but it has to be apparent that the "customer" chunk is an Achilles heel for just about all dotcom-y biz. The ones who aren't getting funded for being gadget new tech, who aren't going to be bought as a team for implementing a possibly-useful technology, are going to have to figure out who the customer is, and from reading HN it seems most are counting on the first two options.